Nakamura, Hideshi published the artcileConvergent and short-step syntheses of dl-Cypridina luciferin and its analogs based on Pd-mediated cross couplings, Safety of (1-tosyl-1H-Indol-3-yl)boronic acid, the publication is Tetrahedron Letters (2000), 41(13), 2185-2188, database is CAplus.
(±)-Cypridina luciferin and its analogs I (X = NH, O, S) were synthesized from 2-aminopyrazine by an eight-step method that included two regio-selective Pd-mediated cross couplings, and their chemi- and bioluminescent activities were compared. Analogs having a 3-benzofuranyl or a 3-benzothienyl group in the place of a 3-indolyl group showed luciferase affinities similar to Cypridina luciferase but with a lower luminescent efficiency, suggesting that the NH group is unimportant for mol. recognition whereas the indolyl group is crucial for efficient luminescence.
Tetrahedron Letters published new progress about 149108-61-2. 149108-61-2 belongs to indole-building-block, auxiliary class Indole,Boronic acid and ester,Sulfamide,Benzene,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (1-tosyl-1H-Indol-3-yl)boronic acid, and the molecular formula is C15H14BNO4S, Safety of (1-tosyl-1H-Indol-3-yl)boronic acid.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles