366017-09-6, Name is Mubritinib, molecular formula is C25H23F3N4O2, belongs to indole-building-block compound, is a common compound. In a patnet, author is Azev, Yurii A., once mentioned the new application about 366017-09-6, Quality Control of Mubritinib.
Quinazoline addition to indole hydrazone derivatives in TFA as a facile synthesis of trifluoroacetylhydrazide quinazoline sigma-adducts
Addition of indole 3-carbaldehyde arylhydrazones to quinazoline in trifluoroacetic acid occurs at the C-5-atom of the indole moiety affording quinazoline sigma-adducts with indole and trifluoroacetylhydrazide moieties.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles