HPLC of Formula: C8H8O2. In 2021 J ETHNOPHARMACOL published article about CENTRAL-NERVOUS-SYSTEM; DEPRESSION; STRESS; ANXIETY; BRAIN in [Kao, Wen-Yi; Lee, Kung-Ta] Natl Taiwan Univ, Dept Biochem Sci & Technol, Taipei 10617, Taiwan; [Kao, Wen-Yi; Ho, Shih-Ching] Dev Ctr Biotechnol, Taipei 11571, Taiwan; [Hsiang, Chien-Yun] China Med Univ, Dept Microbiol & Immunol, Taichung 40402, Taiwan; [Ho, Tin-Yun] China Med Univ, Grad Inst Chinese Med, Taichung 40402, Taiwan in 2021, Cited 43. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.
Ethnopharmacological relevance: Stress is a state of feeling that inhibits one from responding properly in the face of a threat. Agarwood smoke has been used in traditional medicine as a sedative anti-anxious, and anti-restless therapy. Its scent emitted from heat induces people to enter a stable state; however, the underlying molecular effect is still unclear. Aim of the study: This study analyzed novel biological events and gene expression signatures induced by agarwood incense smoke in mice. Materials and methods: Incense smoke was produced by heating at 150 degrees C for 30 min in a headspace autosampler oven. We treated mice with exposure to incense smoke from Kynam agarwood for 45 min/day for 7 consecutive days. After a 7-day inhalation period, the potent agarwood smoke affected-indicators in serum were measured, and the RNA profiles of the mouse brains were analyzed by microarray to elucidate the biological events induced by agarwood incense smoke. Results: Chemical profile analysis showed that the major component in the incense smoke of Kynam was 2-(2phenylethyl) chromone (26.82%). Incense smoke from Kynam induced mice to enter a stable state and increased the levels of serotonin in sera. The emotion-related pathways, including dopaminergic synapse, serotonergic synapse, GABAergic synapse, long-term depression and neuroactive ligand-receptor interaction, were significantly affected by incense smoke. Moreover, the expression of Crhr2 and Chrnd genes, involved with neuroactive ligand-receptor interaction pathway, was upregulated by incense smoke. Conclusions: By a newly-established incense smoke exposure system, we first identified that anti-anxious and antidepressant effects of agarwood incense smoke were likely associated with the increase of serotonin levels and multiple neuroactive pathways in mice.
Welcome to talk about 123-11-5, If you have any questions, you can contact Kao, WY; Hsiang, CY; Ho, SC; Ho, TY; Lee, KT or send Email.. HPLC of Formula: C8H8O2
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles