Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Phenylpyridine, is researched, Molecular C11H9N, CAS is 1008-89-5, about Deliberately Losing Control of C-H Activation Processes in the Design of Small-Molecule-Fragment Arrays Targeting Peroxisomal Metabolism.Quality Control of 2-Phenylpyridine.
1-Biphenylylpyrrolidones,and 2-biphenylyl- and 2-terphenylylpyridines were prepared by photochem. arylation of 1-arylpyrrolidones and 2-arylpyridines with arenediazonium tetrafluoroborates. Combined photochem. arylation, “”nuisance effect”” (SNAr) reaction sequences have been employed in the design of small arrays for immediate deployment in medium-throughput X-ray protein-ligand structure determination Reactions were deliberately allowed to run “”out of control”” in terms of selectivity; for example the ortho-arylation of 2-phenylpyridine gave five products resulting from mono- and bisarylations combined with SNAr processes. As a result, a number of crystallog. hits against NUDT7, a key peroxisomal CoA ester hydrolase, have been identified.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles