Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Computed Properties of https://www.ambeed.com/products/498-02-2.html, 498-02-2, Name is Apocynin, SMILES is O=C(C1=CC=C(O)C(OC)=C1)C, belongs to indole-building-block compound. In a document, author is Kock, Mario, introduce the new discover.
The first synthesis of raputimonoindole A from the tree Raputia praetermissa (Rutaceae) is reported, starting from indole-5-carbaldehyde. The key step is Braun ‘ s diastereoselective Heck-Suzuki cascade that assembled the prenylated methylenetetrahydrofuran moiety. The unsubstituted indole enamine functionality was tolerated, and the absolute configuration of naturally occurring raputimonoindole A is assigned as (R,R). Raputimonoindole B was accessed by Ir-catalyzed C-H activation/borylation followed by Suzuki-Miyaura cross-coupling. Two biosynthetically related 5-(dihydrofuran-2-yl)indole derivatives from R. simulans were synthesized by ring-closing metathesis, and their absolute configurations were determined.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 498-02-2. Computed Properties of https://www.ambeed.com/products/498-02-2.html.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles