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A new series of indole carboxamides have been synthesized through coupling reactions. Several substitutions on the aromatic ring and on the amino acids are well tolerated, and the corresponding indole carboxamides have been obtained with good yields. The same procedure can be also extended to the pyrrole nucleus. Four of these compounds have been screened for their antimicrobial activity against ten different yeast strains and two of them showed an antifungal activity. Further explorations are required to clarify a potential applicability in biological fields.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 6960-45-8, and how the biochemistry of the body works.Application of 6960-45-8

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles