In an article, author is Nunewar, Saiprasad, once mentioned the application of 60-27-5, Name is Creatinine, molecular formula is C4H7N3O, molecular weight is 113.1179, MDL number is MFCD00059730, category is indole-building-block. Now introduce a scientific discovery about this category, Computed Properties of C4H7N3O.
Co(III), Rh(III) & Ir(III)-Catalyzed Direct C-H Alkylation/Alkenylation/Arylation with Carbene Precursors
Metal carbenes play a pivotal role in transition-metal-catalyzed synthetic transfer reactions. The metal carbene is generated either from a diazo compound through facile extrusion of N-2 with a metal catalyst or in situ generated from other sources like triazoles, pyriodotriazoles, sulfoxonium ylides and iodonium-ylide. On the other hand, Co(III), Rh(III) & Ir(III)-catalyzed C-H functionalizations have been well established as a key synthetic step to enable the construction of various synthetic transformations. Interestingly, in recent years, merging of these two concepts C-H activation and carbene migratory insertion gained much attention, in particular group 9 metal-catalyzed arene C-H functionalizations with carbene precursors via carbene migratory insertion. In this review, we summarize recent advances in Co(III), Rh(III) & Ir(III)-catalyzed direct C-H alkylation/alkenylation/arylation with carbene precursors and also discuss key synthetic intermediates within the catalytic cycles.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 60-27-5, Computed Properties of C4H7N3O.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles