Reference of 136-77-6, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 136-77-6, Name is 4-Hexylbenzene-1,3-diol, SMILES is CCCCCCC1=C(O)C=C(O)C=C1, belongs to indole-building-block compound. In a article, author is Li, Xiaocheng, introduce new discover of the category.
Subcellular discriminated distribution under diverse apoptosis phase using a two-photon active probe with indole moiety
Subcellular organelles play critical roles in the process of apoptosis. Fluorescent probes that specifically target different organelles during cell death processes to monitor cell viability has important implications. In this work, two D(donor)-pi-A(acceptor) configuration molecules (A1 and A2) with considerable two-photon absorption cross section in the near infrared region have been rational designed and synthesized. Of note, the obtained two probes could target different organelles in living and fixed cells, respectively. The reasons for different organelles targeting ability of A1 and A2 are discussed in our work. It provides a promising platform for real-time monitoring of cell mortality under subcellular level.
Reference of 136-77-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 136-77-6.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles