15317-58-5, 1H-Indole-3-carbohydrazide is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: Equimolar quantities of compound 2 (1 mmol) and a substituted carboxylic acid were dissolved in phosphoryl chloride (5 mL) and heated at 80C for 3-6 h, the progress of reaction being monitored by TLC. The reaction mixture was then heated under reduced pressure to allow excess phosphoryl chloride to distill off, and the residue was subjected to flash chromatography on silica gel using 15-25% acetone in petroleum ether as eluent to give the target compounds 3a-m (Table 1).
15317-58-5, The synthetic route of 15317-58-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Zhang, Ming-Zhi; Mulholland, Nick; Beattie, David; Irwin, Dianne; Gu, Yu-Cheng; Chen, Qiong; Yang, Guang-Fu; Clough, John; European Journal of Medicinal Chemistry; vol. 63; (2013); p. 22 – 32;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles