With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.162100-42-7,6-Chloro-5-methyl-1H-indole,as a common compound, the synthetic route is as follows.
a) 1-(6-Chloro-5methyl-1H-indol-3-yl)-2,2,2-trifluoro-ethanone; Using a procedure described in J. Med. Chem. 1991, 34, 140, from 0.250 g (0.002 mol) of 6-chloro-5-methyl-1H-indole were prepared 0.38 g (96%) of the title compound as a white solid.
162100-42-7, The synthetic route of 162100-42-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Bissantz, Caterina; Grundschober, Christophe; Ratni, Hasane; Rogers-Evans, Mark; Schnider, Patrick; US2007/21463; (2007); A1;,
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