New learning discoveries about 16732-69-7

16732-69-7, As the paragraph descriping shows that 16732-69-7 is playing an increasingly important role.

16732-69-7, Ethyl 7-bromo-1H-indole-2-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step 1 S-Benzoyl^-bromo-lH-indole^-carboxylic acid ethyl ester To a solution of 7-bromo-lH-indole-2-carboxylic acid ethyl ester (2.04 g, 7.6 mmol) in 1,2- dichloroethane (60 ml) were added AICI3 (2.0 g, 15.0 mmol) and benzoic anhydride (3.45 g, 15.2 mmol). After heating at 9O0C for 2 hours, the reaction mixture was poured into a mixture OfEtOAcZH2O. The organic fraction was separated and washed with water and brine. After drying over MgSO4, the organic fraction was concentrated in vacuo and the resulting residue was purified by flash chromatography to give b-Benzoyl-7-bromo-lH- indole -2 -carboxylic acid ethyl ester as yellow solid (-100%). MS: (M+H)+ 374.1.

16732-69-7, As the paragraph descriping shows that 16732-69-7 is playing an increasingly important role.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/55808; (2008); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles