16732-70-0, Ethyl 5-bromo-1H-indole-2-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of 5-Bromo-lH-indole-2-carboxylic acid ethyl ester (50 mg, 0.186 mmol) and l-fluoro-2,4,6-trimethylpyridinium triflate (204 mg, 0.60 mmol) are dissolved in tetrachloroethane (1 ml) and heated to 100 0C for 30 minutes. The reaction is diluted with ethyl acetate washed with water and brine. The organic layer is dried (sodium sulfate), filtered and concentrated in vacuo to give an oil that is purified by reverse phase EtaPLC to give the title compound as a white solid 27 mg, 50%, LC/MS ESI m/z (M+Eta)+ = 286.31.
16732-70-0, As the paragraph descriping shows that 16732-70-0 is playing an increasingly important role.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ABEYWARDANE, Asitha; FARMER, Bennett; FARROW, Neil Alexander; GAO, Donghong A.; HEIM-RIETHER, Alexander; KEENAN, Lana Louise Smith; MUGGE, Ingo Andreas; TAYLOR, Steven John; XIONG, Zhaoming; YU, Yang; ZHANG, Qiang; WO2010/45188; (2010); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles