26340-49-8, 2-Iodo-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a suspension of NaH (ca. 60wt%, 123 mg, 3.08 mmol) in THF (3 mL) at 0 C was added a solutionof 6 (500 mg, 2.06 mmol) in THF (4 mL). The reaction mixture was stirred at 0 C for 10 min and RTfor 15 min. A solution of TBSCl (466 mg, 3.09 mmol) in THF (3 mL) was added dropwise and thereaction mixture was heated to reflux for 2h. After cooling to RT, the reaction was quenched with H2O(20 mL) and extracted with AcOEt (3 x 30 mL). The organic layers were combined, dried over MgSO4,and concentrated in vacuo. The residue was purified by flash chromatography (silica gel, hexane) toafford 2b (540 mg, 73% yield) as a light yellow oil.
26340-49-8, As the paragraph descriping shows that 26340-49-8 is playing an increasingly important role.
Reference£º
Article; Miyamoto, Hiroshi; Hirano, Tomohiro; Okawa, Yoichiro; Nakazaki, Atsuo; Kobayashi, Susumu; Tetrahedron; vol. 69; 45; (2013); p. 9481 – 9493;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles