31827-04-0, Methyl 3-hydroxy-1H-indole-2-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 184C Methyl 3-isopropoxy-1H-indole-2-carboxylate A solution of potassium tert-butoxide (0.25 g, 2.2 mmol) in DMSO (3 mL) at 0 C. was treated with a solution of Example 184B (0.3 g, 1.57 mmol) in DMSO (5 mL), warmed to room temperature, stirred for 1 hour, treated with 2-bromopropane (0.24 mL, 2.5 mmol), stirred at for 16 hours, and poured into ice/water (30 mL). The precipitate was filtered, washed with water and dried under vacuum at room temperature to provide the desired product (58%). MS (ESI(-)) m/e 232 (M-H)-; 1H NMR (300 MHz, DMSO-d6) delta 1.28 (d, 6H), 3.85 (s, 3H), 4.42-4.52 (m, 1H), 7.04 (t, 1H), 7.25 (t, 1H), 7.36 (d, 1H), 7.59 (d, 1H), 11.30 (s, 1H).
31827-04-0, The synthetic route of 31827-04-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; BaMaung, Nwe Y.; Craig, Richard A.; Kawai, Megumi; Wang, Jieyi; Dai, Yujia; Guo, Yan; Sheppard, George; Verzal, Mary K.; Vasudevan, Anil; Michaelides, Michael; US2002/91148; (2002); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles