467451-91-8, 6-(Trifluoromethoxy)-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,467451-91-8
Oxalyl chloride (0.19 ml, 2.2 mmol, 1.1 eq) was added to (4) (0.40 g, 2.0 mmol, 1.0 eq) in Et2O (5 ml) at O0C. The reaction was allowed to reach room temperature and stirred for 4 h after which time the product was isolated by filtration. The filtrate was evaporated to give further product. The product was washed with Et2O (2 x 10ml) to provide (5) as a yellow solid (0.58 mg, 2.0 mmol, 100%).
467451-91-8 6-(Trifluoromethoxy)-1H-indole 22048958, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Patent; LECTUS THERAPEUTICS LIMITED; KHAN, Nawaz Mohammed; BURCKHARDT, Svenja; CANSFIELD, Julie Elaine; VO, Ngoc-Tri; ARMER, Richard Edward; BOFFEY, Raymond John; WO2010/1179; (2010); A2;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles