Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Wang, Ting-Ting, once mentioned the application of 80-08-0, Name is Dapsone, molecular formula is C12H12N2O2S, molecular weight is 248.3, MDL number is MFCD00007887, category is indole-building-block. Now introduce a scientific discovery about this category, Recommanded Product: 80-08-0.
Versatile synthesis of functionalized beta- and gamma-carbolines via Pd-catalyzed C-H addition to nitriles/cyclization sequences
The first example of versatile synthesis of functionalized beta-carbolines and gamma-carbolines via redox-free Pd-catalyzed C-H addition of indole to nitrile/cyclization sequences is reported. A wide range of functionalized beta-carbolines and gamma-carbolines can be prepared from readily accessible indoles and nitriles in good to excellent yields under the optimal conditions.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles