New learning discoveries about Omeprazole

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In an article, author is Borah, Arun Jyoti, once mentioned the application of 73590-58-6, Recommanded Product: Omeprazole, Name is Omeprazole, molecular formula is C17H19N3O3S, molecular weight is 345.4161, MDL number is MFCD00083192, category is indole-building-block. Now introduce a scientific discovery about this category.

The Rh-catalyzed, remote terminal hydroarylation of active olefins at the C7-position of indoles and the ortho-position of indolines and anilines with the appropriate choice of a N-(PBu2)-Bu-t directing group through long-range deconjugative isomerization has been reported. This transformation not only overcomes the conjugate rule of Michael acceptors but also controls the positional selectivity of indoles, representing a significant advancement in both alkene isomerization and the C-H alkylation of indoles.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles