Related Products of 99409-32-2On September 21, 1998 ,《Application of β-1,4-galactosyltransferase in the synthesis of complex branched-chain oligosaccharide mimics of fragments of the capsular polysaccharide of Streptococcus pneumoniae type 14》 was published in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry. The article was written by Niggemann, Jutta; Kamerling, Johannis P.; Vliegenthart, Johannes F. G.. The article contains the following contents:
The chemoenzymic synthesis is described of β-D-Galp-(1→4)-β-D-Glcp-(1→6)-[β-D-Galp-(1→4)]-β-D-GlcpNAc-(1→O[CH2]3O→4)-β-D-Glcp-(1→OCH2CH:CH2) and β-D-Galp-(1→4)-β-D-GlcpNAc-(1→O[CH2]3O→4)-β-D-Glcp-(1→6)-[β-D-Galp-(1→4)]-β-D-GlcpNAc-(1→O[CH2]3O→4)-β-D-Glcp-(1→OCH2-CH:CH2), representing hexa- and octasaccharide mimics of fragments of the Streptococcus pneumoniae type 14 polysaccharide. In a chem. approach the intermediate linear oligosaccharide mimics I (R1 = CH2CH:CH2; R2 = Q; R3 = H) and I (R2 = Q1) were synthesized, wherein both terminal and non-terminal N-acetyl-β-D-glucosamine residues were not yet galactosylated. The alkyl-bridged derivatives were found to be good acceptor substrates for bovine milk β-1,4-galactosyltransferase. Reaction of the anomeric allyl functions with cysteamine under UV-irradiation gave the corresponding 3-(2-aminoethylthio)propyl glycosides I (R1 = (CH2)3S(CH2)2NH2; R3 = Q) (II) and II (R2 = Q1; R3 = Q) suitable for further coupling of the oligosaccharide mimics to protein carriers. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Related Products of 99409-32-2)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Related Products of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles