A facile and convenient synthesis of 1H-isoindole-1,3(2H)-diones was written by Nikpour, Farzad;Kazemi, Samira;Sheikh, Davood. And the article was included in Heterocycles in 2006.Category: indole-building-block This article mentions the following:
A facile synthesis of 1H-isoindole-1,3(2H)-diones (e.g., I) has been developed by the reaction of the corresponding anhydrides (e.g., II) with potassium cyanate or sodium thiocyanate. The reactions were carried out in neutral media under reflux or under microwave irradiation without use of catalyst. Good to excellent yields of the products were obtained in high purity with very simple work-up. In the experiment, the researchers used many compounds, for example, 4,5,6,7-Tetrabromoisoindoline-1,3-dione (cas: 24407-32-7Category: indole-building-block).
4,5,6,7-Tetrabromoisoindoline-1,3-dione (cas: 24407-32-7) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Category: indole-building-block
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles