Oseka, Maksim et al. published their research in Organic Letters in 2016 | CAS: 112656-95-8

7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Synthetic Route of C8H4N2O4

Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles was written by Oseka, Maksim;Kimm, Mariliis;Kaabel, Sandra;Jarving, Ivar;Rissanen, Kari;Kanger, Tonis. And the article was included in Organic Letters in 2016.Synthetic Route of C8H4N2O4 This article mentions the following:

A highly enantioselective organocatalytic [2,3]-rearrangement of oxindole derivatives is presented. The reaction was catalyzed by squaramide, and this provides access to 3-hydroxy 3-substituted oxindoles I and II (Ar = Ph, 4-ClC6H4, 3-ClC6H4, 2-ClC6H4, 4-MeOC6H4, 4-NO2C6H4, 2-thienyl, 2-naphthyl, etc.; R1 = H, 5-F, 7-F, 5-MeO, 5-Br, 7-NO2, etc.; R2 = H, Bn, Me, i-Pr, 4-MeC6H4CH2) in high enantiomeric purities. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Synthetic Route of C8H4N2O4).

7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Synthetic Route of C8H4N2O4

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles