Indocyanine-Based Activatable Fluorescence Turn-On Probe for γ-Glutamyltranspeptidase and Its Application to the Mouse Model of Colon Cancer was written by Park, Seokan;Lim, Soo-Yeon;Bae, Sang Mun;Kim, Sang-Yeob;Myung, Seung-Jae;Kim, Hae-Jo. And the article was included in ACS Sensors in 2016.SDS of cas: 171429-43-9 This article mentions the following:
An activatable fluorescent probe from indocyanine was developed for the detection of tumor-enriched γ-glutamyltranspeptidase (γGT). The probe exhibited a dramatic fluorescence enhancement (F/F0 = 10) as well as a bathochromic shift (>100 nm) upon the treatment of γGT with a low limit of detection of 0.15 unit/L and was further successfully applied as a sensitive probe for γGT in the mouse model of colon cancer. In the experiment, the researchers used many compounds, for example, 1-(5-Carboxypentyl)-2,3,3-trimethyl-3H-indol-1-ium bromide (cas: 171429-43-9SDS of cas: 171429-43-9).
1-(5-Carboxypentyl)-2,3,3-trimethyl-3H-indol-1-ium bromide (cas: 171429-43-9) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.SDS of cas: 171429-43-9
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles