Pearson, Stuart E’s team published research in Synthesis in 2005-10-04 | 101083-92-5

Synthesis published new progress about Heterocyclization. 101083-92-5 belongs to class indole-building-block, and the molecular formula is C7H5N3O2, Application of C7H5N3O2.

Pearson, Stuart E.; Nandan, Santosh published the artcile< A practical, efficient synthesis of 5-amino-7-azaindole>, Application of C7H5N3O2, the main research area is azaindole reduction Raney nickel; azaindoline preparation nitration; nitro azaindole preparation reduction; nitropyridine amino iodination; iodo amino pyridine preparation Sonogashira reaction acetylene silane; silylacetylaminopyridine preparation heteroannulation; amino azaindole preparation.

A much improved, workable synthesis of 5-amino-7-azaindole is described in 66% overall yield starting from 2-amino-5-nitropyridine. The key stage involves a microwave promoted heteroannulation reaction of a pyridine alkyne.

Synthesis published new progress about Heterocyclization. 101083-92-5 belongs to class indole-building-block, and the molecular formula is C7H5N3O2, Application of C7H5N3O2.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles