On March 31, 1986, Pindur, Ulf; Flo, Camran published an article.Name: Methyl 2-methyl-1H-indole-3-carboxylate The title of the article was Reactions of electron-rich heterocycles with derivatives of carboxylic ortho acids. VII. Regioselective, mild acylation of 2-methylindole with di- and trialkoxycarbenium tetrafluoroborates. A simple procedure for deriving 3-acyl-2-methylindoles and 3-methoxycarbonyl-2-methylindole. And the article contained the following:
The regioselective acylation of 2-methylindole with RC+(OR1)2BF4- (R = H, Me, R1 = Et; R = Ph, R1 = Me; R = OMe, R1 = Me) gave indoles I [R2 = MeCOPhCO,CO2Me). The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Name: Methyl 2-methyl-1H-indole-3-carboxylate
The Article related to methylindole acylation alkoxycarbenium tetrafluoroborate regiochem, indole acyl carboxy, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Name: Methyl 2-methyl-1H-indole-3-carboxylate
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles