Crystal structure of 4-N-phenylisoindolinone, C14H11NO was written by Polamo, M.;Talja, M.. And the article was included in Zeitschrift fuer Kristallographie – New Crystal Structures in 2003.SDS of cas: 5388-42-1 This article mentions the following:
The title compound is monoclinic, space group P21/n, a 5.925(4), b 7.556(2), c 23.11(1) 闂? 闁?94.67(5)闂? Z = 4, Rgt(F) = 0.055, wRref(F2) = 0.140, T = 193 K. At. coordinates are given. The title compound, 4-N-phenylisoindolinone, has a slightly distorted sp2-hybridized nitrogen, the sum of angles at N1 is 359.1闂? Since the Ph ring is almost coplanar to the isoindolinone plane, 9.4(1)闂? a reasonable 闂?interaction could be expected. The bond length of N1-C1 is slightly shorter, 1.421(3) 闂? than in 2-[2,6-bis(1-methylethyl)phenyl]-2,3-dihydro-1H-isoindol-1-one, 1.428(2) 闂? in which 闂?interaction can not exist because the aryl ring adopts perpendicular orientation to the isoindolinone part of the mol. The 闂?interaction of the nitrogen to the Ph ring might also explain the weaker interaction of the nitrogen to the carbonyl group; N1-C2 bond is 1.376(3) 闂? whereas in 2-[2,6-bis(1-methylethyl)phenyl]-2,3-dihydro-1H-isoindol-1-one bond length is 1.358(2) 闂? In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1SDS of cas: 5388-42-1).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.SDS of cas: 5388-42-1
Referemce:
Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles