Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. 19005-93-7, formula is C9H7NO, Name is 1H-Indole-2-carbaldehyde. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings. Recommanded Product: 1H-Indole-2-carbaldehyde.
Prashanthi, M.;Babu, H. Ramesh;Rani, Janapatla Uma research published 《 Design, Synthesis and Molecular Docking Studies of Novel Indole-Isoxazole-Triazole Conjugates as Potent Antibacterial Agents》, the research content is summarized as follows. In search of better antibacterial agents, a series of novel 5-((aryl)methyl)-3-(1H-indol-2-yl)isoxazoles I (R = 3-Cl, 4-OMe, 2,3-Me2, 3,5-Me2, 4-NO2) and 5-((3-chlorophenoxy)methyl)-3-(1-((1-(aryl)-1H-1,2,3-triazol-4-yl)methyl)-1H-indol-2-yl)isoxazoles II (Ar = 4-ClC6H4, 3,5-Cl2C6H3, 4-MeOC6H4, 3-CF3C6H4, 3,5-(MeO)2, 4-ClC6H2) were synthesized in one-pot by using indole-2-carbaldehyde, substituted (prop-2-yn-1-yloxy) benzene and different substituted 1-azidobenzene and further evaluated for their in vitro antibacterial activity. Compound II (Ar = 3-CF3C6H4) showed more potent activity against B. subtilis and S. aureus, whereas, the compound II (Ar = 3,5-Cl2C6H3) showed potent activity against S. aureus when compared with standard streptomycin. Mol. docking studies were also carried out to complement the exptl. results.
Recommanded Product: 1H-Indole-2-carbaldehyde, 1H-Indole-2-carbaldehyde is a useful research compound. Its molecular formula is C9H7NO and its molecular weight is 145.16 g/mol. The purity is usually 95%.
1H-Indole-2-carbaldehyde is a useful research chemical used as a reactant in the synthesis of substituted 2-amino-4H-chromenes and benzochromenes using K2CO3 as catalyst.
1H-Indole-2-carbaldehyde is a solvent that has been used in the protein data and molecular modeling study. The 1H NMR spectrum of this compound showed an intense signal at δ 4.8 ppm, corresponding to the hydroxyl proton. This solvent also has fluorescence properties, as shown by its photophysical and structural analysis. The 1H-indole-2-carbaldehyde molecule has an active methylene group and an oxindole ring with amine substituents., 19005-93-7.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles