Related Products of 27421-51-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.27421-51-8, Name is 1-Methyl-1H-indole-2-carbaldehyde, molecular formula is C10H9NO. In a Article£¬once mentioned of 27421-51-8
Synthesis and preliminary cytotoxicity studies of achiral indolyl-substituted titanocenes
From the reaction of various 6-indolylfulvenes (la-f) with Super Hydride (LiBEt3H), followed by transmetalation with titanium tetrachloride (TiCl4), six indolyl-substituted titanocenes, bis[( 1 -methylindol-2-yl)cyclopentadienyl]titanium(IV) dichloride (3a), bis[( 1 -methyl-5-methoxyindol-2-yl)cyclopentadienyl]titanium(IV) dichloride (3b), a dihydrochloride derivative of bis[(l-methyl3-dimethylaminomethylindol-2-yl) cyclopentadienyl]titanium(IV) dichloride (3c), bis[(l-methylindol-3yl) cyclopentadienyl]titanium(IV) dichloride (3d), bis[(l-methyl-5-methoxyindol-3- yl)cyclopentadienyl]titanium(IV) dichloride (3e), and bis[(l-methylmethoxyindol- 3-yl)cyclopentadienyl]titanium(IV) dichloride (3f), were obtained. The six titanocenes 3a-f were tested for their cytotoxicity through MTT-based in vitro tests on CAKI-I cell lines in order to determine their IC50 values. Titanocenes 3a-f were found to have IC50 values of 47 (¡À9), 15 (¡À2), 8.2 (¡À1.9), 21 (¡À5), 11 (¡À1), and 170 (¡À40) muM, respectively.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 27421-51-8
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles