Authors Mehta, J; Aryal, P; Reddy, VP in WILEY-V C H VERLAG GMBH published article about METAL-FREE; NUCLEOPHILIC TRIFLUOROMETHYLATION; ASYMMETRIC-SYNTHESIS; KETONES; AMINES; IMINES in [Mehta, Jatin; Aryal, Puspa; Prakash Reddy, V.] Missouri Univ Sci & Technol, Dept Chem, Rolla, MO 65409 USA in 2021, Cited 39. Category: indole-building-block. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
The C(sp(2)-H)-trifluoromethylation of hydrazones would give access to the alpha-trifluoromethylated hydrazones that can serve as intermediates in the synthesis of pharmaceutically interesting fluorinated compounds. Herein, we demonstrate the Cu-catalyzed C(sp(2)-H)-trifluoromethylation of the aldehyde hydrazones using the readily available and cost effective Langlois reagent (sodium trifluoromethanesulfinate). This reaction is broadly applicable to a series of aromatic aldehyde N-aminomorpholine hydrazones to give the corresponding C(sp(2))-trifluoromethyl hydrazones in moderate to high yields. The reaction generally tolerates a series of electron-releasing as well as electron-withdrawing substituents on the aromatic ring.
About 4-Methoxybenzaldehyde, If you have any questions, you can contact Mehta, J; Aryal, P; Reddy, VP or concate me.. Category: indole-building-block
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles