The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane(SMILESS: C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1,cas:132098-59-0) is researched.Product Details of 1008-89-5. The article 《Copper(II)-Catalyzed Asymmetric Photoredox Reactions: Enantioselective Alkylation of Imines Driven by Visible Light》 in relation to this compound, is published in Journal of the American Chemical Society. Let’s take a look at the latest research on this compound (cas:132098-59-0).
Copper(II) bis(oxazoline) complexes generated in situ from Cu(BF4)2 and nonracemic bisoxazolines acted as photoredox catalysts in the absence of other sensitizers for enantioselective alkylation reactions of imines such as dioxobenzoisothiazolecarboxylate I and N-Boc imino oxindoles with aralkyltrifluoroborates to yield nonracemic α-amino esters such as benzisothiazolidinecarboxylate II and benzylic oxindoles such as III. The copper-bisoxazoline catalysts both initiated radical generation and governed subsequent stereoselective transformations. The mechanism of the reactions was studied by trapping of radical intermediates, UV/visible spectra and reduction potentials of reactants, intermediates, and catalysts formed in the reactions, and the crystal structure of a dimeric copper bis(oxazoline) catalyst potentially generated under the reaction conditions.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles