Chemistry, like all the natural sciences, Application In Synthesis of Bikinin, begins with the direct observation of nature— in this case, of matter.188011-69-0, Name is Bikinin, SMILES is O=C(O)CCC(NC1=NC=C(Br)C=C1)=O, belongs to indole-building-block compound. In a document, author is Pogosyan, S. A., introduce the new discover.
New substituted spiro[chromene-4,3-indoles] and spiro[indole-3,4-quinolines] have been synthesized in 35-65% yields by one-pot regioselective three-component condensation of N-substituted isatins with two active methylene compounds.
If you are hungry for even more, make sure to check my other article about 188011-69-0, Application In Synthesis of Bikinin.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles