I found the field of Chemistry very interesting. Saw the article Sustainable Synthetic Approaches for 3-Aminoimidazo-fused Heterocycles via Groebke-Blackburn-Bienayme Process published in 2020.0. Safety of 3-Hydroxybenzaldehyde, Reprint Addresses Yamajala, RBRD (corresponding author), SASTRA, Dept Chem, Sch Chem & Biotechnol, Thanjavur 613401, India.. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde
Two different sustainable and efficient synthetic methods have been developed for the synthesis of a variety of 3-aminoimidazo fused heterocycles by one-pot three component reaction of 2-aminoazines, aldehydes and isocyanides. The methods adopted were (a) aqueous micellar mediated condition (method A) (b) VB(1)catalyzed reaction under solvent-free condition (method B). Excellent yields were obtained for a broad range of biologically significant imidazopyridine core molecules under green conditions at room temperature. Synthesis in aqueous micellar medium, mild reaction conditions, organocatalyst, easy work-up and isolation, and gram scale synthesis, are some of the advantages of these protocols.
About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Mathavan, S; Yamajala, RBRD or concate me.. Safety of 3-Hydroxybenzaldehyde
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles