Chemistry, like all the natural sciences, Formula: https://www.ambeed.com/products/611-71-2.html, begins with the direct observation of nature— in this case, of matter.611-71-2, Name is (R)-2-Hydroxy-2-phenylacetic acid, SMILES is [C@@H](O)(C1=CC=CC=C1)C(=O)O, belongs to indole-building-block compound. In a document, author is Song, Jian, introduce the new discover.
A novel palladium(0)-catalyzed intermolecular coupling reaction of 2-gem-dibromovinylanilines and N-tosylhydrazones was reported to construct 2-(1-phenylvinyl)-indoles efficiently. The indole bearing 1, 1-disubstituted alkenes were obtained in one step with short reaction time, in high yields and broad substrate scope. The formed indole derivates could be easily transformed into much more valuable molecules.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 611-71-2. Formula: https://www.ambeed.com/products/611-71-2.html.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles