Prusty, Namrata published the artcileSynthesis and Photophysical Study of Heteropolycyclic and Carbazole Motif: Nickel-Catalyzed Chelate-Assisted Cascade C-H Activations/Annulations, Category: indole-building-block, the main research area is benzoindole preparation; indoline alkyne tandem reaction; polyarylcarbazole preparation regioselective; indole alkyne tandem reaction.
Nickel-catalyzed synthesis of polyarylcarbazoles I (R = H, Me; R1 = 4-F, 4-Cl, 4-Br, 5-Me, 5-OMe; R2 = C2H5, C6H5, 4-FC6H4, etc.) and II (R3 = 6-Br, 7-Cl, 8-Me, etc.) through sequential C-H bond activations has been described. Regioselective indole C2/C3 functionalization has been achieved in the presence of indoles III C7-H, which is quite challenging. In addition, this approach also gives easy access to building a heteropolycyclic motif through C6/C7 C-H functionalization of indolines IV. This methodol. is not limited to aromatic internal alkynes R2CCR2 as coupling partners; aliphatic alkynes have also shown good tolerance. Notably, during the optimization the catalytic enhancement with sodium iodide as an additive has been observed The photophys. properties of these highly conjugated mols. were obtained.
Organic Letters published new progress about C-H bond activation. 41910-64-9 belongs to class indole-building-block, name is 4-Chloroindoline, and the molecular formula is C8H8ClN, Category: indole-building-block.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles