Regiospecific N-Arylation of Aliphatic Amines under Mild and Metal-Free Reaction Conditions was written by Purkait, Nibadita;Kervefors, Gabriella;Linde, Erika;Olofsson, Berit. And the article was included in Angewandte Chemie, International Edition in 2018.SDS of cas: 6872-06-6 This article mentions the following:
A transition metal-free N-arylation of primary and secondary amines with diaryliodonium salts is presented. Both acyclic and cyclic amines are well tolerated, providing a large set of N-alkyl anilines. The methodol. is unprecedented among metal-free methods in terms of amine scope, the ability to transfer both electron-withdrawing and electron-donating aryl groups, and efficient use of resources, as excess substrate or reagents are not required. In the experiment, the researchers used many compounds, for example, 2-Methylindoline (cas: 6872-06-6SDS of cas: 6872-06-6).
2-Methylindoline (cas: 6872-06-6) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.SDS of cas: 6872-06-6
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles