Qin, Qixue published the artcileVisible-Light-Promoted Redox Neutral C-H Amidation of Heteroarenes with Hydroxylamine Derivatives, Name: 4-(Benzyloxy)-1-methyl-1H-indole, the main research area is iridium photocatalyst amidation heteroarene hydroxylamine derivative.
A room temperature redox neutral direct C-H amidation of heteroarenes has been achieved. Hydroxylamine derivatives, which are easily accessed, have been employed as tunable nitrogen sources. These reactions were enabled by a visible-light-promoted single-electron transfer pathway without a directing group. A variety of heteroarenes, such as indoles, pyrroles, and furans, could go through this amidation with high yields (up to 98%). E.g., irradiation of N-methylindole, TsONTsMe, the photocatalyst fac-Ir(ppy), and NaHCO3 in DMF gave 66% amide (I). These reactions are highly regioselective, and all the products were isolated as a single regioisomer.
Organic Letters published new progress about Amidation. 13523-93-8 belongs to class indole-building-block, name is 4-(Benzyloxy)-1-methyl-1H-indole, and the molecular formula is C16H15NO, Name: 4-(Benzyloxy)-1-methyl-1H-indole.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles