A novel, efficient synthesis of 3,3-dimethylindoline was written by Ramsay, T. W.;Slater, G. R.;Smith, P.. And the article was included in Synthetic Communications in 1995.Name: 3,3-Dimethylindoline This article mentions the following:
The Lewis acid mediated cyclization of N-methallylacetanilide, followed by hydrolysis gave 3,3-dimethylindoline in excellent yield. In the experiment, the researchers used many compounds, for example, 3,3-Dimethylindoline (cas: 1914-02-9Name: 3,3-Dimethylindoline).
3,3-Dimethylindoline (cas: 1914-02-9) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Name: 3,3-Dimethylindoline
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles