Antibacterial and cytotoxic activity of 3, 3′-(5,5′-methylene bis(3-mercapto-4H-1,2,4-triazole-5,4-diyl) bis (azan-1-yl-1-ylidene) diindolin-2-ones was written by Rani, S. Shobha;Ajitha, M.;Agaiah, Bairi;Sarangapani, M.. And the article was included in Journal of Chemical and Pharmaceutical Sciences in 2010.Related Products of 112656-95-8 This article mentions the following:
Indolinones I (R1 = H, R2 = 5-F, 5-Me, 6-Br, etc.) were synthesized by the condensation of an appropriate isatin with 5,51-methylenediyl-bis(4-amino-4H-1,2,4-triazole-3-thiol). Compounds I were screened for cytotoxic activity using A-549 Lung cancer and HT-29 Colon cancer cell lines by MTT method and antibacterial activity against B. subtilis, S. aureus, E. coli and S. typhi by cup plate method. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Related Products of 112656-95-8).
7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Related Products of 112656-95-8
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles