Rassi, Somayeh; Baharfar, Robabeh published the artcile< Synthesis of indole based amides using immobilized lipase on graphene oxide (GO@lipase) as a retrievable heterogeneous nano biocatalyst>, HPLC of Formula: 399-76-8, the main research area is lipase immobilized graphene oxide catalyst preparation thermal stability; indolyl carboxylic acid benzaldehyde alkyl isocyanide lipase Passerini reaction; phenyl alkylamino oxoethyl indolyl carboxylate preparation green chem.
A green and efficient one-pot procedure to achieved indole based amides using Passerini reaction involving indole-2-carboxylic acids, benzaldehydes and alkyl isocyanides in the presence of immobilized lipase on graphene oxide as a heterogeneous nano biocatalyst was developed. This method has the advantages of simple operation, mild reaction conditions and good to excellent yields. The features of this method are highlighted by using a retrievable nanostructure catalyst. This process was asserted to be efficient in the synthesis of indole derivatives
Polyhedronpublished new progress about Amides Role: BPN (Biosynthetic Preparation), BIOL (Biological Study), PREP (Preparation). 399-76-8 belongs to class indole-building-block, and the molecular formula is C9H6FNO2, HPLC of Formula: 399-76-8.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles