Microwave-induced one pot synthesis of fluorinated spiro [indole-pyrimidines] was written by Sachdeva, Harshita. And the article was included in Indian Journal of Heterocyclic Chemistry in 2009.Quality Control of 7-Nitroindoline-2,3-dione This article mentions the following:
A series of fluorinated spiro[indole-pyrimidines] were synthesized in 75-85% yields by rapid and highly efficient one-pot microwave-induced technique involving condensation of 3-aroylmethylene-2H-indol-ones with fluorinated phenylthioureas using ethanol as energy transfer medium. Aroylmethylene-indolones was synthesized in situ by the reaction of substituted indole-2,3-diones and fluorinated acetophenones. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Quality Control of 7-Nitroindoline-2,3-dione).
7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Quality Control of 7-Nitroindoline-2,3-dione
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles