An article Highly Phototoxic Transplatin-Modified Distyryl-BODIPY Photosensitizers for Photodynamic Therapy WOS:000591679100001 published article about SINGLET OXYGEN GENERATION; CHARGE-TRANSFER; IN-VITRO; PHOTOCHEMICAL PROPERTIES; RATIONAL DESIGN; MESO-PHENYL; DYES; CANCER; BORON; SOLVENT in [Padrutt, Roxane; Babu, Vipin; Klingler, Simon; Kalt, Martina; Schumer, Frank; Anania, Maria I.; Schneider, Lukas; Spingler, Bernhard] Univ Zurich, Dept Chem, Winterthurerstr 190, CH-8057 Zurich, Switzerland in 2021, Cited 67. Name: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
We report the synthesis of the first transplatin-BODIPY conjugates for application in photodynamic therapy (PDT). The distyryl BODIPYs containing two iodine atoms were designed to absorb in the red region, easily undergo intersystem crossing for efficient singlet oxygen generation, and additionally offer the possibility for coordination with mono-activated transplatin. We were able to demonstrate that coordination of the BODIPYs with a mono-activated transplatin increases the phototoxic index of the photosensitizers significantly, giving rise to highly phototoxic distyryl BODIPY derivatives, of which one was shown to have the highest ever reported phototoxic index against any cell line. Furthermore, the photophysical mechanism of singlet oxygen generation in distyryl BODIPYs undergoing intramolecular charge transfer was studied experimentally and using time-dependent density functional theory.
Welcome to talk about 123-11-5, If you have any questions, you can contact Padrutt, R; Babu, V; Klingler, S; Kalt, M; Schumer, F; Anania, MI; Schneider, L; Spingler, B or send Email.. Name: 4-Methoxybenzaldehyde
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,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles