An article Synthesis of Bridged Biaryl Atropisomers via Sequential Cu- and Pd-Catalyzed Asymmetric Ring Opening and Cyclization WOS:000471212100015 published article about CHIRAL NATURAL-PRODUCTS; ENANTIOSELECTIVE SYNTHESIS; HECK; DIARYLIODONIUM in [Gu, Zhenhua] Univ Sci & Technol China, Dept Chem, Ctr Excellence Mol Synth, 96 Jinzhai Rd, Hefei 230026, Anhui, Peoples R China; Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, 96 Jinzhai Rd, Hefei 230026, Anhui, Peoples R China in 2019, Cited 28. Category: indole-building-block. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1
Bridged biaryl atropisomers are important units in bioactive molecules. A synthesis of lactone-bridged biaryl atropisomers was realized by a Cu-catalyzed asymmetric ring-opening/acyoxylation of cyclic diaryliodoniums, followed by a palladium-catalyzed diastereoselective cyclization. It was found that a catalytic amount of Cu(OTf)(2) served as an additive to promote the palladium-catalyzed Heck cyclization.
About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Xue, XP; Gu, ZH or concate me.. Category: indole-building-block
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles