On March 20, 2003, Seifert, Joachim; Singh, Latika; Ramsdale, Tracie Elizabeth; West, Michael Leo; Drinnan, Nicholas Barry published a patent.Reference of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside The title of the patent was Synthetic heparin pentasaccharides via glycosylation reaction using different protecting groups. And the patent contained the following:
Synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids. Thus, heparin pentasaccharide I (R1 = SO3Na) was prepared via glycosylation reaction using different protecting groups. The experimental process involved the reaction of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside(cas: 130539-43-4).Reference of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside
The Article related to heparinoid synthon uronate pentasaccharide preparation glycosylation protecting group, uronate heparin oligosaccharide preparation monosaccharide disaccharide trisaccharide and other aspects.Reference of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles