Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 5-Bromo-2-phenyl-1H-indole. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 83515-06-4
The invention relates to a can be used as pharmaceutical intermediates shown in the following formula (III) indole compound synthesis method, the method comprises in a solvent and an inert gas atmosphere, the catalyst, nitrogen-containing ligand and the presence of acid promoter, the following formula (I) compound with the following formula (II) compound generating reaction, after-treatment after the reaction, so as to obtain states the type (III) compound, Wherein R1 Selected from H or halogen; R2 Is selected from H, C1 – C6 Alkyl, C1 – C6 Alkoxy or halogen, or R2 With the substituted phenyl together form a naphthyl. A method through a suitable substrate, catalyst, nitrogen-containing ligand, and the solvent of the acid promoter such as coordination with the comprehensive selection, thereby expanding the range of the substrate, and can be good yields aryl substituted indole compound, thus in the field of organic chemical synthesis has good application prospect and research value, for this kind of compound synthesis provides new method. (by machine translation)
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 5-Bromo-2-phenyl-1H-indole, you can also check out more blogs about83515-06-4
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles