A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of Methyl 1-methyl-1H-indole-5-carboxylate, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 128742-76-7, Name is Methyl 1-methyl-1H-indole-5-carboxylate, molecular formula is C11H11NO2. In a Patent, authors is ，once mentioned of 128742-76-7
The invention discloses a formula (I) containing the structure shown as the imidazole fused three-ring compound or its pharmaceutically acceptable salt or a stereoisomer thereof or its prodrug molecule. The compound has adjusting IDO1 active role, such compounds by blocking immune checkpointing IDO1, T cell activation can be enhanced, used for the treatment of IDO1 mediated immune suppression, thus can become effective drug for the treatment of malignant tumor. With the checkpointing the antibody of the protein drug or other anti-cancer drugs share, can enhance the anti-cancer effects. At the same time also has the potential to effectively treat with IDO1 related with the immunosuppressive disease, have high application value. (by machine translation)
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 128742-76-7, help many people in the next few years.Safety of Methyl 1-methyl-1H-indole-5-carboxylate
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles