Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Formula: C14H11N, Which mentioned a new discovery about 16096-33-6
Indole and indoline derivatives were selectively and temperature dependently synthesized via the intramolecular cross-coupling reaction between the amino and aromatic bromine functionalities of 2-bromophenethylamine derivatives in the presence of 10% palladium on carbon (Pd/C), 1,1-bis(diphenylphosphino)ferrocene (DPPF), and sodium tert-butoxide (NaO-t-Bu) in mesitylene at 140 and 200C, respectively. The neutralization using acetic acid after formation of the indoline derivatives effectively promoted their aromatization, and the corresponding indole derivatives were obtained at 140C. Furthermore, various aryl groups were also introduced to the N-1 position of the indole, pyrrole, and carbazole rings by their direct intramolecular arylation with aryl halides and a one-pot protocol for N-arylindole synthesis from 2-bromophenethylamine was developed.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 16096-33-6, help many people in the next few years.Formula: C14H11N
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles