The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade, the main research direction is dioxane thiane oxathiane preparation diastereoselective regioselective; alkyne aldehyde hydroacylation conjugate addition tandem rhodium.Reference of 1,4-Dibromobutane.
Rhodium-catalyzed hydroacylation using alkynes substituted with pendant nucleophiles, delivers linear α,β-unsaturated enone intermediates with excellent regioselectivity. These adducts are used to construct a broad range of diversely substituted, saturated O-, N- and S-heterocycles in a one-pot process. Judicious choice of cyclisation conditions enabled isolation of O-heterocycles with high levels of diastereoselectivity. A variety of derivatization reactions are also performed, generating functionalized hydroacylation products. This sequence serves as a general approach for the synthesis of fully saturated heterocycles.
From this literature《Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade》,we know some information about this compound(110-52-1)Reference of 1,4-Dibromobutane, but this is not all information, there are many literatures related to this compound(110-52-1).
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles