1196-70-9, 1H-Indole-6-carbaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 55. Synthesis of compound 2882-(2,6-dimethylpyridin-4-yloxy)acetohydrazide (100 mg, 0.51 mmol) and 1 H-indol-6- carbaldehyde (74 mg, 0.51 mmol) were dissolved in EtOH 2 mL, followed by stirring at 110 C for 12 hours. The reaction mixture was added with water, and extracted with ethyl acetate. The obtained organic layer was dried over magnesium sulfate, and purified by columnchromatography (hexane:ethyl acetate = 2:1) to obtain Compound 288 (30 mg, 18 %).?H NMR (400 MHz, DMSO-d6): oe 11.43 (m, 1H), 11.28 (m, 1H), 8.35-8.07 (2s, 1H), 7.68 (d, J= 18.0 Hz, 1H), 7.57 (d, J- 8.4 Hz, 1H), 6.66 (d, J= 22.0 Hz, 2H), 6.47 (s, 1H), 5.20 (s, H),4.69 (s, 1H), 2.34 (m, 6H).
The synthetic route of 1196-70-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CHONG KUN DANG PHARMACEUTICAL CORP.; INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION; CHOI, HoJin; LEE, JaeWon; LEE, ChangGon; HA, NiNa; SEO, Su Kil; LEE, SunMi; LEE, Song-Min; WO2014/35149; (2014); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles