2795-41-7, 6-Fluoroindole-3-carboxaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a stirred solution of ketone 9b (50 mg, 0.34 mmol) andaldehyde (0.34 mmol) in anhydrous EtOH, piperidine (144.9 mg,1.72 mmol) was slowly added. After stirring for 10 h at 80 C, thereaction mixture was concentrated and extracted with CH2Cl2(3 20 mL). The combined organic layers were then washed withbrine, dried over anhydrous Na2SO4, and concentrated in vacuo toprovide the crude product, which was purified by column chromatography with petroleum/ethyl acetate (4:1) to give thecorresponding pure compounds 18a-i., 2795-41-7
The synthetic route of 2795-41-7 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Xu, Feijie; Li, Wenlong; Shuai, Wen; Yang, Limei; Bi, Yi; Ma, Cong; Yao, Hequan; Xu, Shengtao; Zhu, Zheying; Xu, Jinyi; European Journal of Medicinal Chemistry; vol. 173; (2019); p. 1 – 14;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles