The synthetic route of 393553-57-6 has been constantly updated, and we look forward to future research findings.
393553-57-6, 6-Bromo-4-methoxy-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Description 8. 6-Ethenyl-4-(methyloxy)-1 H-indole (D8) To a solution of 6-bromo-4-(methyloxy)-1 H-indole (900 mg, 3.98 mmol) in 1 ,2- dimethoxyethane (20 ml_) was added tributylvinyltin (1.74 ml_, 5.96 mmol). The reaction mixture was degassed with argon and then treated with dichlorobis(tri-o tolylphosphine)palladium (153 mg, 0.19 mmol). The mixture was heated at 9O0C for 65 hours. The mixture was filtered through a pad of celite, washed with ethyl acetate and then the filtrate concentrated in vacuo. The product was purified by silica gel chromatography eluting with 2-50% ethyl acetate in hexane to yield the title compound (D8), (781 mg). LC-MS: MH+ = 174 (CnH11NO = 173), 393553-57-6
The synthetic route of 393553-57-6 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; GLAXO GROUP LIMITED; WO2009/103710; (2009); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles