Chemistry is an experimental science, Formula: C10H10BrN, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 10075-49-7, Name is 5-Bromo-1,3-dimethyl-1H-indole
Enantioselective Friedel-Crafts alkylation for synthesis of 2-substituted indole derivatives
An efficient catalytic asymmetric intermolecular C2 Friedel-Crafts alkylation reaction between N-methyl skatole and beta,gamma-unsaturated alpha-ketoesters has been realized by a chiral N,N?-dioxide-Ni(ii) complex. The corresponding indole derivatives were obtained in good yield (up to 96%) with excellent enantioselectivities (up to 99% ee) under mild reaction conditions.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C10H10BrN, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10075-49-7, in my other articles.
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles