5192-03-0, 1H-Indol-5-amine is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Using procedure A: 2-Amino-3,5-dibromo-pyrazine (100 mg) and 5-aminoindole (200 mg) yielded 150 mg of a 1 :1 mixture of 5-aminoindole and the desired product MS m/z 303 [M + H]+ which was used without further purification or characterization.; Procedure A:General procedure for SNAgamma on 2-amino-3,5-dibromo-pyrazine2-Amino-3,5-dibromo-pyrazine, triethylamine (3 equiv) and the appropiate amine or alcohol (3 equiv) were dissolved in 4 mL water and the resulting mixture was heated to 195 0C for 1 hour. Water and ethyl acetate were added and the phases separated. The water phase was extracted once more with ethyl acetate. The combined organic phases were washed (water and brine) and concentrated to yield a crude mixture of product and unre- acted amine or alcohol. This crude mixture was used without further purification or characterization in the subsequent Suzuki reaction.
5192-03-0, The synthetic route of 5192-03-0 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; BIOVITRUM AB (publ); WO2009/95399; (2009); A2;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles